- SARS-CoV-2 suppresses mRNA splicing, translation, and protein trafficking in a multipronged mechanism to evade host defences
Banerjee AK*, Blanco MR*, Bruce EA*, Honson DD**, Chen L**, Chow A**, Bhat P, Ollikainen N, Quinodoz SA, Loney C, Thai J, Miller ZD, Lin AE, Schmidt MM, Stewart DG, Goldfarb D, De Lorenzo G, Rihn SJ, Voorhees R, Botten JW, Majumdar D†, and Guttman M†
Cell 2020
*co-first author, **co-second author, †corresponding author - Direct RT-qPCR detection of SARS-CoV-2 RNA from patient nasopharyngeal swabs without an RNA extraction step
Bruce, EA*#, Huang, M#, Perchetti, GA, Tighe, S, Laaguiby, P, Hoffman, JJ, Gerrard, DL, Nalla, AK, Wei, Y, Greninger, AL, Diehl, SA, Shirley, DJ, Leonard, DGB, Huston, CD, Kirkpatrick, BD, Dragon, JA, Crothers, JW, Jerome, KR*†, Botten, JW *†
PLoS Biology 2020
*corresponding author, #contributed equally, †senior authors and made equivalent contributions - ‘All in’: a pragmatic framework for COVID-19 testing and action of a global scale
Pettit SD*, Jerome KR, Rouquié D, Mari B, Barbry P, Kanda Y, Matsumoto M, Hester S, Wehmas L, Botten JW, Bruce EA
EMBO Mol Med 2020 - The use of novel epitope-tagged arenaviruses reveals that Rab5c-positive endosomal membranes are targeted by the LCMV matrix protein
Ziegler CM‡, Bruce EA‡, Kelly JA, King BR, Botten JW*
Journal of General Virology 2018
‡ Co-first author - The major cellular sterol regulatory pathway is required for pathogenic hantavirus infection
Petersen J‡, Drake MJ‡, Bruce EA‡, Riblett AM, Didigu CA, Wilen CB, Malani N, Male F, Lee FH, Bushman FD, Cherry S, Doms RW, Bates P* , Briley K*
PLoS Pathogens 2014
‡ Co-first author - The genetics of virus particle shape in equine influenza A virus
Elton D, Bruce EA, Bryant N, Wise HM, MacRaea S, Rash A, Smith N, Turnbull ML, Medcalf L, Daly JM, Digard P*
Influenza and other respiratory viruses 2013 - Role of the Rab11 pathway in negative-strand virus assembly
Bruce EA*, Stuart A, McCaffrey MW, Digard P
Biochemical Society Transactions 2012 - A Rab11- and microtubule-dependent mechanism for cytoplasmic transport of influenza A virus viral RNA
Amorim MJ‡, Bruce EA‡, Read EK, Foeglein A, Mahen R, Stuart AD, Digard P*
Journal of Virology 2011
‡ Co-first author - The Rab11 pathway is required for influenza A virus budding and filament formation
Bruce EA, Digard P, Stuart AD*
Journal of Virology 2010
Bruce Lab 