Bruce Lab Papers
- Surveillance of Vermont wildlife in 2021-2022 reveals no detected SARS-CoV-2 viral RNA
Despres HW, Mills MG, Schmidt MM, Gov J, Perez Y, Jindrich M, Crawford AML, Kohl WT, Rosenblatt E, Kubinski HC, Simmons BC, Nippes MC, Goldenberg AJ, Murtha KE, Nicoloro S, Harris MJ, Feeley AC, Gelinas TK, Cronin MK, Frederick RS, Thomas M, Johnson ME, Murphy J, Lenzini EB, Carr PA Jr, Berger DH, Mehta SP, Floreani CJ, Koval AC, Young AL, Fish JH, Wallace J, Chaney E, Ushay G, Ross RS, Vostal EM, Thisner MC, Gonet KE, Deane OC, Pelletiere KR, Rockafeller VC, Waterman M, Barry TW, Goering CC, Shipman SD, Shiers AC, Reilly CE, Duff AM, Madruga SL, Shirley DJ, Jerome KR, Pérez-Osorio AC, Greninger AL, Fortin N, Mosher BA†, Bruce EA†
Sci Rep 2023
†corresponding author, Bruce lab trainees - Viral infectivity in paediatric SARS-CoV-2 clinical samples does not vary by age.
Schmidt MM, Despres HW, Shirley DJ, Bose ME, McCaul KC, Crothers JW, Henrickson KJ, Lee B, Bruce EA†
Access Microbiol 2023
†corresponding author, Bruce lab trainees - Measuring infectious SARS-CoV-2 in clinical samples reveals a higher viral titer:RNA ratio for Delta and Epsilon vs. Alpha variants
Despres HW*, Mills MG*, Shirley DJ, Schmidt MM, Huang ML, Roychoudhury P, Jerome KR, Greninger AL, Bruce EA†
Proc Natl Acad Sci U S A. 2022
*co-first author, †corresponding author, Bruce lab trainees - Predicting infectivity: comparing four PCR-based assays to detect culturable SARS-CoV-2 in clinical samples
Bruce EA*†, Mills MG*, Sampoleo R, Perchetti GA, Huang ML, Despres HW, Schmidt MM, Roychoudhury P, Shirley DJ, Jerome KR, Greninger AL†, Botten JW†
EMBO Mol Med. 2022
*co-first author, †corresponding author, Bruce lab trainees
Key Prior Papers
- SARS-CoV-2 suppresses mRNA splicing, translation, and protein trafficking in a multipronged mechanism to evade host defences
Banerjee AK*, Blanco MR*, Bruce EA*, Honson DD**, Chen L**, Chow A**, Bhat P, Ollikainen N, Quinodoz SA, Loney C, Thai J, Miller ZD, Lin AE, Schmidt MM, Stewart DG, Goldfarb D, De Lorenzo G, Rihn SJ, Voorhees R, Botten JW, Majumdar D†, and Guttman M†
Cell 2020
*co-first author, **co-second author, †corresponding author - Direct RT-qPCR detection of SARS-CoV-2 RNA from patient nasopharyngeal swabs without an RNA extraction step
Bruce, EA*#, Huang, M#, Perchetti, GA, Tighe, S, Laaguiby, P, Hoffman, JJ, Gerrard, DL, Nalla, AK, Wei, Y, Greninger, AL, Diehl, SA, Shirley, DJ, Leonard, DGB, Huston, CD, Kirkpatrick, BD, Dragon, JA, Crothers, JW, Jerome, KR*†, Botten, JW *†
PLoS Biology 2020
*corresponding author, #contributed equally, †senior authors and made equivalent contributions - ‘All in’: a pragmatic framework for COVID-19 testing and action of a global scale
Pettit SD*, Jerome KR, Rouquié D, Mari B, Barbry P, Kanda Y, Matsumoto M, Hester S, Wehmas L, Botten JW, Bruce EA
EMBO Mol Med 2020 - The use of novel epitope-tagged arenaviruses reveals that Rab5c-positive endosomal membranes are targeted by the LCMV matrix protein
Ziegler CM‡, Bruce EA‡, Kelly JA, King BR, Botten JW*
Journal of General Virology 2018
‡ Co-first author - The major cellular sterol regulatory pathway is required for pathogenic hantavirus infection
Petersen J‡, Drake MJ‡, Bruce EA‡, Riblett AM, Didigu CA, Wilen CB, Malani N, Male F, Lee FH, Bushman FD, Cherry S, Doms RW, Bates P* , Briley K*
PLoS Pathogens 2014
‡ Co-first author - The genetics of virus particle shape in equine influenza A virus
Elton D, Bruce EA, Bryant N, Wise HM, MacRaea S, Rash A, Smith N, Turnbull ML, Medcalf L, Daly JM, Digard P*
Influenza and other respiratory viruses 2013 - Role of the Rab11 pathway in negative-strand virus assembly
Bruce EA*, Stuart A, McCaffrey MW, Digard P
Biochemical Society Transactions 2012 - A Rab11- and microtubule-dependent mechanism for cytoplasmic transport of influenza A virus viral RNA
Amorim MJ‡, Bruce EA‡, Read EK, Foeglein A, Mahen R, Stuart AD, Digard P*
Journal of Virology 2011
‡ Co-first author - The Rab11 pathway is required for influenza A virus budding and filament formation
Bruce EA, Digard P, Stuart AD*
Journal of Virology 2010
Bruce Lab 